Raf-B Polyclonal Antibody, 100ul[BT-AP07630] Cell Senescence Mutations in this gene and

Mutations in this gene and a highly similar gene located nearby

indicates nucleotide deletion in the genomic sequence would result in frameshift and early termination of translation

DNA-binding protein that specifically recognize the sequence 5'-YAAC

Continual translation of the mRNA under conditions of eukaryotic translation initiation factor 2A inactivation is thought to create a feedback loop for reactivation of the gene during recovery from stress

cold and modulation of intracellular pH

Raf-B Polyclonal Antibody, 100ul[BT-AP07630] Cell Senescence Mutations in this gene andBRAF (B Raf proto oncogene, serine threonine kinase) encodes a protein belonging to the raf mil family of serine threonine protein kinases. This protein plays a role in regulating the MAP kinase ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in BRAF are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance.