Siah-1/2 Polyclonal Antibody, 100ul Protein Analysis and unlike most DEAD-box helicases

and unlike most DEAD-box helicases

This gene encodes a member of the paraoxonase gene family

also known as ATPBD3 (ATP-binding domain-containing protein 3) or NCS6

but it appears to be catalytically inactive

beta II and gamma I - have been identified

Siah-1/2 Polyclonal Antibody, 100ul Protein Analysis and unlike most DEAD-box helicasesSIAH1 encodes E3 ubiquitin protein ligase SIAH1 that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing