Mouse Hypoxia-inducible Factor 1Α, HIF-1A ELISA Kit, 96T Centrifuges This gene has a pseudogene

This gene has a pseudogene on chromosome 18

Isoform 8 regulates the activity of Ca(+2) released-activated Ca(+2) (CRAC) Channels in T-cells

enhance ligand-dependent activity of estrogen receptors alpha and beta

The nAChRs are (hetero)pentamers composed of homologous subunits

Mutations in this gene result in Hartnup disorder

Mouse Hypoxia-inducible Factor 1Α, HIF-1A ELISA Kit, 96T Centrifuges This gene has a pseudogeneFunctions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis