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PAR4 Polyclonal Antibody, 100ul[BT-AP12783] Site-directed Mutagenesis The 20S core is composed

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PAR4 Polyclonal Antibody, 100ul[BT-AP12783] Site-directed Mutagenesis The 20S core is composedThe tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1 interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.

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Description

The 20S core is composed of 4 rings of 28 non-identical subunits| 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits

Component of the DREAM complex (also named LINC complex) at least composed of E2F4| E2F5| LIN9| LIN37| LIN52| LIN54| MYBL1| MYBL2| RBL1| RBL2| RBBP4| TFDP1 and TFDP2

Two protein-coding transcripts and one non-protein coding transcript have been found for this gene

This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs)

The gamma 3 chain is most similar to the gamma 1 chain

PAR4 Polyclonal Antibody, 100ul[BT-AP12783] Site-directed Mutagenesis The 20S core is composedThe tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1 interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.

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