IKK beta(Phospho Tyr188) Polyclonal Antibody, 20ul DNA Oligo Synthesis The gene product is important

The gene product is important for continuation of T cell activation

Mutations in this gene cause Charcot-Marie-Tooth disease| type 2A1

it localizes to the cytoplasm of dendrites and is also enriched in the nucleus where it interacts with the RNA polymerase III transcriptional repressor Maf1 to regulate gamma-aminobutyric acid A receptor surface expression

and a hydrophobic region

CASP8 cleaves BH3-interacting domain death agonist

IKK beta(Phospho Tyr188) Polyclonal Antibody, 20ul DNA Oligo Synthesis The gene product is importantThe protein encoded by this gene phosphorylates the inhibitor in the inhibitor NF kappa B complex, causing dissociation of the inhibitor and activation of NF kappa B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein coding and some not, have been found for this gene.