Axl Polyclonal Antibody, 50ul[BT-AP00783] Peptide Synthesis Multiple transcript variants encoding different

Multiple transcript variants encoding different isoforms have been found for this gene| but the biological validity of some variants has not been determined

Polymorphisms in this protein appear to be tissue specific and influence protease targeting

with a strong preference for the latter

MALT1 and this protein are thought to synergize in the activation of NF-kappaB

The protein encoded by LEPR belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins

Axl Polyclonal Antibody, 50ul[BT-AP00783] Peptide Synthesis Multiple transcript variants encoding differentThe protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3 Axl Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin like motifs at the N terminal, followed by two fibronectin type III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K dependent protein growth arrest specific 6 (Gas6).