PERK(Phospho Thr981) Polyclonal Antibody, 50ul Nucleic Acid Amplification Mutations in this gene have

Mutations in this gene have been associated with autosomal dominant high myopia (MYP24)

2003 [PubMed 14508493])

The enzyme encoded by this gene degrades type IV and V collagens

It is the vertebrate homologue of the yeast protein Mex67p

The protein encoded by this gene is part of the SMN complex

PERK(Phospho Thr981) Polyclonal Antibody, 50ul Nucleic Acid Amplification Mutations in this gene haveThe protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in