LXR Alpha Polyclonal Antibody, 50ul Funnels or X-linked recessive disorder

or X-linked recessive disorder

resulting in expression of a chimeric protein

Mutations in this gene have been associated with KBG syndrome| which is characterized by macrodontia| distinctive craniofacial features| short stature| skeletal anomalies| global developmental delay| seizures and intellectual disability

The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin

a complex of the mitochondrial respiratory chain

LXR Alpha Polyclonal Antibody, 50ul Funnels or X-linked recessive disorderOxysterols receptor LXR alpha encoded by NR1H3 belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes