MDMX(Phospho Ser367) Polyclonal Antibody, 100ul Pipette Controller reducing fatigue and offering a

reducing fatigue and offering a smoother

It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel

Downregulation of expression of this gene by promoter hypermethylation has been observed in a wide spectrum of human malignancies

Contains 1 SAM (sterile alpha motif) domain

When defective

MDMX(Phospho Ser367) Polyclonal Antibody, 100ul Pipette Controller reducing fatigue and offering aThis gene encodes a nuclear protein that contains a p53 binding domain at the N terminus and a RING finger domain at the C terminus, and shows structural similarity to p53 binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation