NR1D2 Polyclonal Antibody, 20ul Cell Screening and Imaging Heme oxygenase activity is induced

Heme oxygenase activity is induced by its substrate heme and by various nonheme substances

Between human and mouse

Mutations in MBTPS2 have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome)

Involved in apoptotic release of cytochrome c

Research supports a transcriptionally active role for the gene and a functional role for the peptide in specific cells

NR1D2 Polyclonal Antibody, 20ul Cell Screening and Imaging Heme oxygenase activity is inducedThis gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.