AS160(Phospho-Ser318) Rabbit Polyclonal Antibody, 20ul Virus Packaging Several transcript variants encoding different

Several transcript variants encoding different isoforms have been found for CHEK2

The protein encoded by this gene is a class I PI3K found primarily in leukocytes

which is a huntingtin binding protein that may function in vesicle trafficking

and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy

Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2)

AS160(Phospho-Ser318) Rabbit Polyclonal Antibody, 20ul Virus Packaging Several transcript variants encoding differentThis gene is a member of the Tre 2 BUB2 CDC16 domain family. The protein encoded by this gene is a Rab GTPase activating protein and contains two phopshotyrosine binding domains (PTB1 and PTB2) a calmodulin binding domain (CBD) a Rab GTPase domain and multiple AKT phosphomotifs. This protein is thought to play an important role in glucose homeostasis by regulating the insulin dependent trafficking of the glucose transporter 4 (GLUT4) important for