RFWD3 Polyclonal Antibody, 100ul DNA Fragments In mouse an alternatively spliced

In mouse an alternatively spliced form of this protein has been shown to act as a cytokine and can induce the production of the inflammatory cytokine IL6 in osteoblasts

ADGRB2 (adhesion G protein-coupled receptor B2) encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family

BCL10 (B-cell CLL/lymphoma 10) was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma

This gene encodes a G protein-coupled receptor (GPCR) that belongs to the oxoglutarate receptor family within the GPCR superfamily

This gene encodes a member of the neurexin protein family

RFWD3 Polyclonal Antibody, 100ul DNA Fragments In mouse an alternatively splicedRFWD3, also named as RNF201, is a E3 ubiquitin protein ligase that mediates the ubiquitination of p53 TP53 in the late response to DNA damage, and acts as a positive regulator of p53 TP53 stability, thereby regulating the G1 S DNA damage checkpoint. RFWD3 may act by catalyzing the formation of short polyubiquitin chains on p53 TP53 that are not targeted to the proteasome. In response to ionizing radiation, It interacts with MDM2 and enhances p53 TP53