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PGE synthase Polyclonal Antibody, 20ul sgRNA Oligos Caspase 9 can undergo autoproteolytic

SKU: 27089046926

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PGE synthase Polyclonal Antibody, 20ul sgRNA Oligos Caspase 9 can undergo autoproteolyticProstaglandin E synthase encoded by PTGES is a glutathione dependent prostaglandin E synthase. The expression of PTGES has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that PTGES may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain

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Description

Caspase 9 can undergo autoproteolytic processing and activation by the apoptosome

May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53

This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB

Mutations in DES are associated with desmin-related myopathy

with the first two cysteines being adjacent to each other

PGE synthase Polyclonal Antibody, 20ul sgRNA Oligos Caspase 9 can undergo autoproteolyticProstaglandin E synthase encoded by PTGES is a glutathione dependent prostaglandin E synthase. The expression of PTGES has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that PTGES may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain

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