MFSD8 Polyclonal Antibody, 100ul Tubes HIST1H1A is intronless and encodes

HIST1H1A is intronless and encodes a replication-dependent histone that is a member of the histone H1 family

composed of a ligand-binding extracellular domain with cysteine-rich region

The N-terminus is poorly conserved and may impart additional roles in developmental regulation| senescence| tumor suppression| cell growth control| and chemotaxis to each member of the family

where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development

|The C-terminus of p100 might be involved in cytoplasmic retention| inhibition of DNA-binding by p52 homodimers| and/or transcription activation

MFSD8 Polyclonal Antibody, 100ul Tubes HIST1H1A is intronless and encodesThis gene encodes a ubiquitous integral membrane protein that contains a transporter domain and a major facilitator superfamily (MFS) domain. Other members of the major facilitator superfamily transport small solutes through chemiosmotic ion gradients. The substrate transported by this protein is unknown. The protein likely localizes to lysosomal membranes. Mutations in this gene are correlated with a variant form of late infantile onset neuronal