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NEIL1 Polyclonal Antibody, 100ul Microplate Mixer Mutations in this gene can

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NEIL1 Polyclonal Antibody, 100ul Microplate Mixer Mutations in this gene canNEIL1 is a member of the Nei endonuclease VIII like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease

Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene

the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of

Alternative splicing

The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase

NEIL1 Polyclonal Antibody, 100ul Microplate Mixer Mutations in this gene canNEIL1 is a member of the Nei endonuclease VIII like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene.

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