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TBC1D4(Phospho Thr642) Polyclonal Antibody, 100ul Immunoassays and probably has a role

SKU: 27371158530

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TBC1D4(Phospho Thr642) Polyclonal Antibody, 100ul Immunoassays and probably has a roleThis gene is a member of the Tre 2 BUB2 CDC16 domain family. The protein encoded by this gene is a Rab GTPase activating protein and contains two phopshotyrosine binding domains (PTB1 and PTB2) a calmodulin binding domain (CBD) a Rab GTPase domain and multiple AKT phosphomotifs. This protein is thought to play an important role in glucose homeostasis by regulating the insulin dependent trafficking of the glucose transporter 4 (GLUT4) important for

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Description

and probably has a role in controlling the excitability of motor neurons

The encoded protein may play a role in neurodegenerative diseases

|PTM:Subsequent to MAP3K14-dependent serine phosphorylation| p100 polyubiquitination occurs then triggering its proteasome-dependent processing

GO annotations related to this gene include nucleic acid binding and ubiquitin protein ligase binding

This gene is located in the cystatin locus and encodes a cysteine proteinase inhibitor found in saliva

TBC1D4(Phospho Thr642) Polyclonal Antibody, 100ul Immunoassays and probably has a roleThis gene is a member of the Tre 2 BUB2 CDC16 domain family. The protein encoded by this gene is a Rab GTPase activating protein and contains two phopshotyrosine binding domains (PTB1 and PTB2) a calmodulin binding domain (CBD) a Rab GTPase domain and multiple AKT phosphomotifs. This protein is thought to play an important role in glucose homeostasis by regulating the insulin dependent trafficking of the glucose transporter 4 (GLUT4) important for

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