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JAK2(Phospho Tyr570) Polyclonal Antibody, 20ul Vacuum Filter The protein encoded by this

SKU: 27391982321

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JAK2(Phospho Tyr570) Polyclonal Antibody, 20ul Vacuum Filter The protein encoded by thisThis gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

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Description

The protein encoded by this gene is an activator of MAP3K7/TAK1| which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK

This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation

WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD)

This protein has been shown to bind the calcium/calmodulin-dependent serine protein kinase (MAGUK family) protein (also known as CASK) and proposed to regulate higher-order brain functions in mammals

macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES)

JAK2(Phospho Tyr570) Polyclonal Antibody, 20ul Vacuum Filter The protein encoded by thisThis gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

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