Rb Polyclonal Antibody, 20ul[BT-AP07689] DNA Libraries Synthesis Designed to be compatible with

Designed to be compatible with VT1

as well as some non-protein coding variants

An important paralog of this gene is GPR139

and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria

integral membrane protein

Rb Polyclonal Antibody, 20ul[BT-AP07689] DNA Libraries Synthesis Designed to be compatible withRB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.