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AFF4 Polyclonal Antibody, 20ul Plates & Dishes TKFC is a member of

SKU: 27630605726

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AFF4 Polyclonal Antibody, 20ul Plates & Dishes TKFC is a member ofThe protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5; 11)(q31; q31q23).

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Description

TKFC is a member of the family of dihydroxyacetone kinases

Two transcript variants resulting from alternative splicing have been identified

Studies in rat indicate that the protein is translated from a non-AUG translation initiation site

which are related to growth

the beta-subunit of the L-type calcium channels

AFF4 Polyclonal Antibody, 20ul Plates & Dishes TKFC is a member ofThe protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5; 11)(q31; q31q23).

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