Histone H2B Polyclonal Antibody, 100ul[BT-AP09963] Serum Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms have been reported

Potently inhibits angiogenesis and tumor growth

Cleavage abolishes NF-kappa-B activation and enhances pro-apototic signaling through the TRADD-FADD interaction

This gene encodes a protein that appears to belong to a family of evolutionarily related proteins (DUF78)

PTM:Glycosylated

Histone H2B Polyclonal Antibody, 100ul[BT-AP09963] Serum Alternatively spliced transcript variants encodingH2BFS is a Pseudogene. Histone H2B type 1 H is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones, also called histone