KCNK4 (TRAAK) Polyclonal Antibody, 50ul Cryopreservation Mutations in this gene cause

Mutations in this gene cause X-linked Charcot-Marie-Tooth disease

• 3 acceleration level & 4 level deceleration

It highly expressed in the duodenal brush border membrane

Gene expression is high during fetal development and in most tumors

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2

KCNK4 (TRAAK) Polyclonal Antibody, 50ul Cryopreservation Mutations in this gene causeThis gene encodes a member of the TWIK related arachidonic acid stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia