USP50 Polyclonal Antibody, 100ul Recombinant Protein Mutations in ITCH are a

Mutations in ITCH are a cause of syndromic multisystem autoimmune disease

Similarity to the RAS suppressor protein| as well as expression down-regulation observed in tumor cells| suggests that it may function as a tumor suppressor

expansion of which is responsible for dentatorubral and pallidoluysian atrophy

Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes

which bridge between the doublet microtubules in axonemes

USP50 Polyclonal Antibody, 100ul Recombinant Protein Mutations in ITCH are aThe ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP50 (ubiquitin specific peptidase 50) is a 339 amino acid protein that belongs