Pax-2 Polyclonal Antibody, 50ul In vitro Transcription is activated by phosphatidylinositol-3

is activated by phosphatidylinositol-3

It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner| suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling

1-10μl volumes

This gene encodes a member of the nuclear distribution E (NudE) family of proteins

where it phosphorylates nuclear targets

Pax-2 Polyclonal Antibody, 50ul In vitro Transcription is activated by phosphatidylinositol-3PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of PAX2 results in multiple