Ret Polyclonal Antibody, 50ul[BT-AP07760] Peripheral Blood Separation Tube Its phosphorylation enhances its transactivation

Its phosphorylation enhances its transactivation and transcriptional activities

Three transcript variants encoding different isoforms have been found for TFAP2A

The protein encoded by this gene contains a C-terminal RING finger domain

The encoded protein interacts with other SR proteins to modulate splice site selection

and thermoregulation

Ret Polyclonal Antibody, 50ul[BT-AP07760] Peripheral Blood Separation Tube Its phosphorylation enhances its transactivationRET, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine