BNIP-3 Polyclonal Antibody, 100ul[BT-AP00949] Immune Cell Analysis The mRNA for this gene

The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination

Acting as a GTPase activating protein (GAP)

and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin

while long expansions of this tract result in spinocerebellar ataxia-2

Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities

BNIP-3 Polyclonal Antibody, 100ul[BT-AP00949] Immune Cell Analysis The mRNA for this geneBNIP3 is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro apoptotic factor. The BCL2 interacting protein 3 interacts with anti apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation.