RFX5 Rabbit Polyclonal Antibody, 50ul Glassware Sets Two alternatively spliced transcript variants

Two alternatively spliced transcript variants encoding distinct proteins have been described

The beta subunit is a non-DNA binding regulatory subunit

There are four major classes

Specific isoforms bind to alpha-dystroglycan

This gene encodes a protein that interacts with the small GTPase rab11

RFX5 Rabbit Polyclonal Antibody, 50ul Glassware Sets Two alternatively spliced transcript variantsA lack of MHC II expression results in a severe immunodeficiency syndrome called MHC II deficiency or the bare lymphocyte syndrome (BLS; MIM 209920). At least 4 complementation groups have been identified in B cell lines established from patients with BLS. The molecular defects in complementation groups B C and D all lead to a deficiency in RFX a nuclear protein complex that binds to the X box of MHC II promoters. The lack of RFX binding activity in