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CD28 Polyclonal Antibody, 100ul General Lab Use Mutations in this gene cause

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CD28 Polyclonal Antibody, 100ul General Lab Use Mutations in this gene causeT cell specific surface glycoprotein CD28 encoded by CD28 is essential for T cell proliferation and survival, cytokine production, and T helper type 2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Description

Mutations in this gene cause some autosomal recessive forms of Brody disease

as only a minority of individuals showed biased expression from the maternal allele (PMID: 8267611)

giving rise to several mRNA species

In response to cytokines and growth factors

and SAM (sterile alpha motif) domains

CD28 Polyclonal Antibody, 100ul General Lab Use Mutations in this gene causeT cell specific surface glycoprotein CD28 encoded by CD28 is essential for T cell proliferation and survival, cytokine production, and T helper type 2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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