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Human Acid Sphingomyelinase-like Phosphodiesterase 3B, SMPDL3B ELISA Kit , 96T Bottle-Top Dispenser subunit:Interacts with EPS15

SKU: 28165764209

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Human Acid Sphingomyelinase-like Phosphodiesterase 3B, SMPDL3B ELISA Kit , 96T Bottle-Top Dispenser subunit:Interacts with EPS15Lipid modulating phosphodiesterase (PubMed: 26095358). Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll like receptor signaling (By similarity). Has in vitro phosphodiesterase activity, but the physiological substrate is unknown (PubMed: 26095358). Lacks activity with phosphocholine containing lipids, but can cleave CDP choline, and

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Description

subunit:Interacts with EPS15

some of which do not encode a protein with a predicted signal peptide

Negatively regulates its own expression and the expression of DBP and BHLHE41/DEC2

enteropathy

It is an imprinted gene| expressed only from the paternal allele| and epigenetic changes at this locus are associated with Wilms tumour| Beckwith-Wiedemann syndrome| rhabdomyosarcoma| and Silver-Russell syndrome

Human Acid Sphingomyelinase-like Phosphodiesterase 3B, SMPDL3B ELISA Kit , 96T Bottle-Top Dispenser subunit:Interacts with EPS15Lipid modulating phosphodiesterase (PubMed: 26095358). Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll like receptor signaling (By similarity). Has in vitro phosphodiesterase activity, but the physiological substrate is unknown (PubMed: 26095358). Lacks activity with phosphocholine containing lipids, but can cleave CDP choline, and

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