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CD6 Polyclonal Antibody, 100ul[BT-AP01522] Human Genome Knockout Libraries thus| it functions as a

SKU: 28169162804

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CD6 Polyclonal Antibody, 100ul[BT-AP01522] Human Genome Knockout Libraries thus| it functions as aCD6 (CD6 molecule) encodes a protein found on the outer membrane of T lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. CD6 product is important for continuation of T cell activation. CD6 may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants

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Description

thus| it functions as a regulator of a wide variety of downstream proteins| including tumor suppressor proteins p53 and BRCA1| checkpoint kinase CHK2| checkpoint proteins RAD17 and RAD9| and DNA repair protein NBS1

Similar genes in zebrafish and mouse have been shown to regulate the transcription of genes that control the production of motile cilia

including a non-AUG (CUG) codon

This gene encodes a male meiotic metaphase chromosome-associated acidic protein

the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors

CD6 Polyclonal Antibody, 100ul[BT-AP01522] Human Genome Knockout Libraries thus| it functions as aCD6 (CD6 molecule) encodes a protein found on the outer membrane of T lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. CD6 product is important for continuation of T cell activation. CD6 may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants

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