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IL-8RBeta Polyclonal Antibody, 100ul[BT-AP04518] Thermal Control Available sequence data analyses identified

SKU: 28249698270

4.9
PLN123.75 PLN163.75

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IL-8RBeta Polyclonal Antibody, 100ul[BT-AP04518] Thermal Control Available sequence data analyses identifiedThe protein encoded by CXCR2 is a member of the G protein coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G protein activated second messenger system. This receptor also binds to chemokine (C X C motif) ligand 1 (CXCL1 MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum dependent

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Description

Available sequence data analyses identified splice variants that differ in the 5' UTR

Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype

This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori

allergic rhinitis

Alternate transcriptional splice variants| encoding different isoforms| have been characterized

IL-8RBeta Polyclonal Antibody, 100ul[BT-AP04518] Thermal Control Available sequence data analyses identifiedThe protein encoded by CXCR2 is a member of the G protein coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G protein activated second messenger system. This receptor also binds to chemokine (C X C motif) ligand 1 (CXCL1 MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum dependent

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