AIRE-1 Polyclonal Antibody, 50ul[BT-AP00312] DNA Oligo Synthesis This gene is the putative

This gene is the putative transforming gene of avian sarcoma virus 17

Alternatively spliced transcript variants encoding different isoforms have been found in GABRA4

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The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation

Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene

AIRE-1 Polyclonal Antibody, 50ul[BT-AP00312] DNA Oligo Synthesis This gene is the putativeAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein (autoimmune regulator) plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with