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MYLK Polyclonal Antibody, 100ul[BT-AP05707] Endonucleases & Exonucleases and the polyA addition motif

SKU: 28346850303

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MYLK Polyclonal Antibody, 100ul[BT-AP05707] Endonucleases & Exonucleases and the polyA addition motifMYLK, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. MYLK encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein

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Description

and the polyA addition motif

Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein| and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1

Mutations in this gene cause mitochondrial complex III deficiency

for this protein

have been reported to be involved in chromosomal translocations in T-cell leukemia

MYLK Polyclonal Antibody, 100ul[BT-AP05707] Endonucleases & Exonucleases and the polyA addition motifMYLK, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. MYLK encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein

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