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FAK(Phospho Tyr397) Polyclonal Antibody, 100ul RNA Synthesis KLF10 (Kruppel like factor 10)

SKU: 28381286349

4.8
EUR141.00 EUR187.00

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FAK(Phospho Tyr397) Polyclonal Antibody, 100ul RNA Synthesis KLF10 (Kruppel like factor 10)This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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Description

KLF10 (Kruppel like factor 10) encodes a member of a family of proteins that feature C2H2-type zinc finger domains

The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family

It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors

Stimulates cancer-associated fibroblast (CAF) proliferation by a rapid genomic response through the EGFR/ERK transduction pathway

GFAP encodes one of the major intermediate filament proteins of mature astrocytes

FAK(Phospho Tyr397) Polyclonal Antibody, 100ul RNA Synthesis KLF10 (Kruppel like factor 10)This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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