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GPS2 Polyclonal Antibody, 100ul Centrifugal Filter Expression is slightly down-regulated by

SKU: 28389572790

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GPS2 Polyclonal Antibody, 100ul Centrifugal Filter Expression is slightly down-regulated byGPS2 encodes G protein pathway suppressor 2 involved in G protein mitogen activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS and MAPK mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1 HDAC3 (nuclear receptor corepressor 1 histone deacetylase 3)

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Description

Expression is slightly down-regulated by dexamethasone and slightly up-regulated by IL-10

this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES

E74 like ETS transcription factor 5 encoded by ELF5 is a member of an epithelium-specific subclass of the Ets transcritpion factor family

This protein binds specifically to the F1 alpha subunit and is thought to prevent this subunit from forming nonproductive homooligomers during enzyme assembly

including stimulation of DNA repair

GPS2 Polyclonal Antibody, 100ul Centrifugal Filter Expression is slightly down-regulated byGPS2 encodes G protein pathway suppressor 2 involved in G protein mitogen activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS and MAPK mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1 HDAC3 (nuclear receptor corepressor 1 histone deacetylase 3)

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