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c-Fms(Phospho Tyr561) Polyclonal Antibody, 50ul Molecular Biology CUL2 not CUL3

SKU: 28531893771

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c-Fms(Phospho Tyr561) Polyclonal Antibody, 50ul Molecular Biology CUL2 not CUL3The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1 PDGF

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Description

CUL2 not CUL3

which catalyzes the removal of the 3' trailer from precursor tRNAs

the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS

The encoded protein appears to aid in both myosin II assembly during cell spreading and disassembly of focal adhesions

Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia

c-Fms(Phospho Tyr561) Polyclonal Antibody, 50ul Molecular Biology CUL2 not CUL3The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1 PDGF

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