SRPK2 Polyclonal Antibody, 100ul Liquid Handling ＆Storage Defects in this gene may

Defects in this gene may be a cause of autosomal recessive spinocerebellar ataxia-10

Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype

GPR171 is a gene on chromosome 3q25

The protein is also involved in cell growth and differentiation

It is a type I membrane protein

SRPK2 Polyclonal Antibody, 100ul Liquid Handling ＆Storage Defects in this gene mayCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,cofactor: Magnesium.,enzyme regulation: Activated by phosphorylation on Ser 52 and Ser 588.,Phosphorylates RS domain containing proteins, such as SFRS1 and SFRS2 on serine residues. Role in spliceosome assembly and in mediating the trafficking of splicing factors. Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral