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IRF-3(Phospho Ser386) Polyclonal Antibody, 50ul Vortex Mixer shown previously to interact with

SKU: 28571700218

4.3
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IRF-3(Phospho Ser386) Polyclonal Antibody, 50ul Vortex Mixer shown previously to interact withThis gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been

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Description

shown previously to interact with the cytosolic domain of mouse Cl-/HCO3- anion exchanger 1 (kAE1) but not erythroid AE1 (eAE1) by a yeast-two hybrid assay

The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs)

The 2'-5'-oligoadenylate synthetase 2 is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2'

This gene encodes TBP

endometrial cancer

IRF-3(Phospho Ser386) Polyclonal Antibody, 50ul Vortex Mixer shown previously to interact withThis gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been

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