FoxO4 (Acetyl Lys407) Rabbit Polyclonal Antibody, 50ul Cell Function Analysis as well as increased surface
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FoxO4 (Acetyl Lys407) Rabbit Polyclonal Antibody, 50ul Cell Function Analysis as well as increased surfacedisease: A chromosomal aberration involving FOXO4 is found in acute leukemias. Translocation t(X; 11)(q13; q23) with MLL HRX. The result is a rogue activator protein. Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin response elements (IREs) and can activate transcription of IGFBP1. Down regulates expression of HIF1A and suppresses hypoxia induced transcriptional activation of HIF1A modulated genes.
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