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An important paralog of this gene is LRRTM2

resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair

It also contains a destruction box (D box) that is required for its degradation by the APC

This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family

GRHPR Rabbit Polyclonal Antibody, 20ul Custom DNA Oligos Experience precision filtration with thisThis gene encodes an enzyme with hydroxypyruvate reductase glyoxylate reductase and D glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene.