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HLA-DQB1/2 Polyclonal Antibody, 100ul Endonucleases & Exonucleases Mutations in this gene are

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HLA-DQB1/2 Polyclonal Antibody, 100ul Endonucleases & Exonucleases Mutations in this gene areHLA DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: b lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26 28 kDa and it

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Description

Mutations in this gene are associated with autism spectrum disorders

In pancreatic tumoral cells

The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity

This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization

HLA-DQB1/2 Polyclonal Antibody, 100ul Endonucleases & Exonucleases Mutations in this gene areHLA DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: b lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26 28 kDa and it

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