PDHK1(Phospho Tyr243) Rabbit Polyclonal Antibody, 100ul[BT-AP11860] DNA Libraries Synthesis A related solute carrier family

A related solute carrier family 11 protein gene is located on chromosome 2

which then phosphorylates and inactivates components of the apoptotic machinery

and with Stickler syndrome

Several transcript variants encoding different isoforms have been described for this gene

Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer

PDHK1(Phospho Tyr243) Rabbit Polyclonal Antibody, 100ul[BT-AP11860] DNA Libraries Synthesis A related solute carrier familyPyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced