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p53(Phospho Thr18) Polyclonal Antibody, 20ul Live Cell Imaging Alternate transcriptional splice variants of

SKU: 29022208645

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p53(Phospho Thr18) Polyclonal Antibody, 20ul Live Cell Imaging Alternate transcriptional splice variants ofThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Alternate transcriptional splice variants of CACNA2D4 have been observed but have not been thoroughly characterized

and impaired glucose metabolism

Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene

modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2

which is involved in multi-drug resistance

p53(Phospho Thr18) Polyclonal Antibody, 20ul Live Cell Imaging Alternate transcriptional splice variants ofThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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