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TWIK-2 Polyclonal Antibody, 100ul Digital Burette CUL4A and COP1

SKU: 29431053954

4.5
USD141.00 USD177.00

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TWIK-2 Polyclonal Antibody, 100ul Digital Burette CUL4A and COP1KCNK6 (potassium two pore domain channel subfamily K member 6) encodes one of the members of the superfamily of potassium channel proteins containing two pore forming P domains. This channel protein, considered an open rectifier, is widely expressed. It is stimulated by arachidonic acid, and inhibited by internal acidification and volatile anaesthetics.

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Description

CUL4A and COP1

Upon phosphorylation| this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement

The encoded protein shares 100% sequence identity with the mouse and rat counterparts

It is also required for normal sperm development

The encoded protein localizes to the Golgi apparatus and may play a role in spermatogenesis

TWIK-2 Polyclonal Antibody, 100ul Digital Burette CUL4A and COP1KCNK6 (potassium two pore domain channel subfamily K member 6) encodes one of the members of the superfamily of potassium channel proteins containing two pore forming P domains. This channel protein, considered an open rectifier, is widely expressed. It is stimulated by arachidonic acid, and inhibited by internal acidification and volatile anaesthetics.

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