PIAS 1 Polyclonal Antibody, 100ul Enzyme Activity Assays an autosomal recessive disease associated

an autosomal recessive disease associated with a susceptibility to pyogenic infections

nine epidermal growth factor repeats

This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14

The WNT gene family consists of structurally related genes which encode secreted signaling proteins

This enzyme may play a role in bone mineralization

PIAS 1 Polyclonal Antibody, 100ul Enzyme Activity Assays an autosomal recessive disease associatedPIAS1 encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Protein inhibitor of activated STAT 1 plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript