CD6 Polyclonal Antibody, 100ul[BT-AP01830] Metabolic enzymes tool compounds Inhibits differentiation of CD34+ cell

Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro)

the Sec7 domain contains guanine-nucleotide exchange protein activity

The product of this gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes

The protein is a member of the tripartite motif (TRIM) family

|mass spectrometry:Monoisotopic| not modified PubMed:16457589|PTM:Acetylated on Lys-5| Lys-8 and Lys-12 during interphase

CD6 Polyclonal Antibody, 100ul[BT-AP01830] Metabolic enzymes tool compounds Inhibits differentiation of CD34+ cellThe C C motif chemokine receptor 7 encoded by CCR7 is a member of the G protein coupled receptor family. This receptor was identified as a gene induced by the Epstein Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic