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Beclin-1 Polyclonal Antibody, 20ul[BT-AP14447] Variant Libraries GFRA4 is a candidate gene

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Beclin-1 Polyclonal Antibody, 20ul[BT-AP14447] Variant Libraries GFRA4 is a candidate geneThis gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

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Description

GFRA4 is a candidate gene for RET-associated diseases

The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma

Subunits lacking these cysteine residues are classified as beta-subunits (Groot Kormelink and Luyten| 1997

Trisomy 13

Both the alpha and delta loci include V (variable)| J (joining)| and C (constant) segments and the delta locus also includes diversity (D) segments

Beclin-1 Polyclonal Antibody, 20ul[BT-AP14447] Variant Libraries GFRA4 is a candidate geneThis gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

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