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SPTC2 Rabbit Polyclonal Antibody, 100ul Lysosome a protein involved in nucleotide

SKU: 29702319080

4.6
PLN123.75 PLN168.75

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SPTC2 Rabbit Polyclonal Antibody, 100ul Lysosome a protein involved in nucleotideThis gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase which consists of two different subunits is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal 5 prime phosphate dependent condensation of L serine and palmitoyl CoA to 3 oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.

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Description

a protein involved in nucleotide excision repair

The encoded protein is a zinc-dependent metallopeptidase that catalyzes the removal of an amino acid from the amino terminus of a protein or peptide

The encoded preproprotein is produced in the hypothalamus and cleaved to generate the mature factor| known as somatoliberin| which acts to stimulate growth hormone release from the pituitary gland

An important paralog of this gene is GPR21

DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al

SPTC2 Rabbit Polyclonal Antibody, 100ul Lysosome a protein involved in nucleotideThis gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase which consists of two different subunits is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal 5 prime phosphate dependent condensation of L serine and palmitoyl CoA to 3 oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.

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