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BRD1 Rabbit Polyclonal Antibody, 20ul Vacuum Filter |Contains 1 collagen IV NC1

SKU: 29724403114

4.8
USD97.20 USD139.20

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BRD1 Rabbit Polyclonal Antibody, 20ul Vacuum Filter |Contains 1 collagen IV NC1This gene encodes a bromodomain containing protein that localizes to the nucleus and can interact with DNA and histone tails. The encoded protein is a component of the MOZ MORF acetyltransferase complex and can stimulate acetylation of histones H3 and H4, thereby potentially playing a role in gene activation. Variation in this gene is associated with schozophrenia and bipolar disorder in some study populations. Alternative splicing results in multiple

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Description

|Contains 1 collagen IV NC1 (C-terminal non-collagenous) domain

A 117 kb microdeletion at the 5' end of the HOXD gene cluster| which includes this gene and the HOXD9-HOXD13 genes| causes synpolydactyly| a dominantly inherited disease resulting in limb malformation

Interacts with CUL4B and DDB1

|Belongs to the transcription factor STAT family

Alternatively spliced transcript variants have been described for LAIR2

BRD1 Rabbit Polyclonal Antibody, 20ul Vacuum Filter |Contains 1 collagen IV NC1This gene encodes a bromodomain containing protein that localizes to the nucleus and can interact with DNA and histone tails. The encoded protein is a component of the MOZ MORF acetyltransferase complex and can stimulate acetylation of histones H3 and H4, thereby potentially playing a role in gene activation. Variation in this gene is associated with schozophrenia and bipolar disorder in some study populations. Alternative splicing results in multiple

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