NFκB-p65(Phospho Ser276) Polyclonal Antibody, 50ul Bio-Reaction Tube ABCC12 is a member of

ABCC12 is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein (ATP binding cassette subfamily C member 12) contains two ATP-binding domains and 12 transmembrane regions

Pharmacodynamics

Mutations in CEP57 cause mosaic variegated aneuploidy syndrome

The enzyme encoded by this gene catalyzes the first mannosylation step in the biosynthesis of lipid-linked oligosaccharides

as well as of certain signal transduction receptors and effectors

NFκB-p65(Phospho Ser276) Polyclonal Antibody, 50ul Bio-Reaction Tube ABCC12 is a member ofNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of this gene, RELA. Four