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Human Insulin-like Growth Factor 2 MRNA-binding Protein 2, IGF2BP2 ELISA Kit, 96T Syringe Filter Supports IL-2 independent and IL-4

SKU: 29886825499

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Human Insulin-like Growth Factor 2 MRNA-binding Protein 2, IGF2BP2 ELISA Kit, 96T Syringe Filter Supports IL-2 independent and IL-4RNA binding factor that recruits target transcripts to cytoplasmic protein RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA mediated degradation (By similarity). Binds to the 5' UTR of the Insulin like growth factor 2 (IGF2) mRNAs. Binding

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Description

Supports IL-2 independent and IL-4 independent growth of helper T-cells

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to generate fructoselysine-3 phosphate (PubMed: 11016445

Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma

They also have different biochemical properties and developmental profiles

Human Insulin-like Growth Factor 2 MRNA-binding Protein 2, IGF2BP2 ELISA Kit, 96T Syringe Filter Supports IL-2 independent and IL-4RNA binding factor that recruits target transcripts to cytoplasmic protein RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA mediated degradation (By similarity). Binds to the 5' UTR of the Insulin like growth factor 2 (IGF2) mRNAs. Binding

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